A Tunable Genetic Switch Based on RNAi and Repressor Proteins for Regulating Gene Expression in Mammalian Cells

The Portal is a joint project of MATTO and the MTTC. The development and implementation of the portal has been paid for by the MTTC, Beth Israel Deaconess Medical Center, Boston Biomedical Research Institute, Boston University, Brandeis University, Caritas St. Elizabeth's Medical Center, Boston Children's Hospital, Dana Farber Cancer Institute, Harvard University, Joslin Diabetes Center, Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, McLean Hospital, Northeastern University, The Schepens Eye Research Institute, and Tufts University.

Intellectual Property

ID:		06-80
IP Type:		Licensable Technology
Title:		A Tunable Genetic Switch Based on RNAi and Repressor Proteins for Regulating Gene Expression in Mammalian Cells
Inventor:		Collins, James J
Summary:		A system for tight, tunable control of mammalian gene expression that couples repressor proteins and a novel RNAi target design that effectively turns any gene off. The technology is endowed with modular capabilities that allow for the regulation of any gene, as well as having the potential to to be utilized in a tissue-specific manner.
Tech Type:		Research Tools \| Drug Discovery Tools
URL:		http://ctf-fmfe.bu.edu/BU0680.pdf
Contact:		Hong Xu, cives@bu.edu, 617 358 4550
Organization:		Boston University

Display all intellectual properties for Collins, James J
Display all intellectual properties for Boston University