anti-metalloendopeptidase EC 3.4.24.15, clone IVD6 (Thop-1 monoclonal antibody)

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Intellectual Property

ID:		03-83
IP Type:		Licensable Technology
Title:		anti-metalloendopeptidase EC 3.4.24.15, clone IVD6 (Thop-1 monoclonal antibody)
Inventor:		Abraham, Carmela R
Summary:		Monoclonal antibody for metalloendopeptidase EC 3.4.24.15 (MP24.15). The investigators have discovered the functional relationship between metalloendopeptidase EC 3.4.24.15 (MP24.15) and the amyloid precursor protein involved in Alzheimer's disease (AD) and that the enzyme promotes A-beta degradation. " Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
Tech Type:		Research Reagents
URL:		http://ctf-fmfe.bu.edu/BU0383.pdf
Contact:		April Effort, chofmann@bu.edu, 617 353 7631
Organization:		Boston University

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