A method for the accurate measure of thin layered structures in X-ray computer tomography.

The Portal is a joint project of MATTO and the MTTC. The development and implementation of the portal has been paid for by the MTTC, Beth Israel Deaconess Medical Center, Boston Biomedical Research Institute, Boston University, Brandeis University, Caritas St. Elizabeth's Medical Center, Boston Children's Hospital, Dana Farber Cancer Institute, Harvard University, Joslin Diabetes Center, Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, McLean Hospital, Northeastern University, The Schepens Eye Research Institute, and Tufts University.

Intellectual Property

ID:		11315
IP Type:		Licensable Technology
Title:		A method for the accurate measure of thin layered structures in X-ray computer tomography.
Inventor:		Reilly, John J.; Silverman, Edwin ; Westin, Carl-Fredrik ; Kikinis, Ron ; Estepar, Raul San Jose; Washko, George
Summary:		The Technology: The inventors have created a new technique for CT image analysis which provides accurate, reproducible quantitative measurement of thin-layered and fine structures. Applications: In addition to drug screening applications, this method can be used in the following clinical: - Measurement of airway wall thickness in the lungs, which correlate with clinical indices of such lung diseases as COPD. - Quantitative assessments of coronary artery narrowing for diagnosis of heart disease and evaluation of disease progression. - Quantification of lung nodule size. - Quantitative assessments of the amount of cartilage in normal and injured joints. Advantages: - This technique provides accurate measurement of very small structures, which is not possible using current edge detection methods. - Because this new method is less subject to image noise than currently available techniques, it may require a lower radiation dose for image acquisition than what is currently required. - The method is adaptable to any make or model CT scanner. Publications: R. San Jose Estepar, G. Washko, E. Silverman, J. Reilly, R. Kikinis, C-F Westin, Accurate Airway Wall Estimation Using Phase Congruency, Lecture Notes in Computer Science, vol. 4191, pp. 125-134, 2006
Tech Type:		Medical Imaging
URL:		http://www.partners.org/techtransfer/availabletechnologies/default.asp
Contact:		Andrew Warner, AJWARNER@partners.org, 617-954-9380
Organization:		Brigham and Women's Hospital

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